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Article type: Impact Factor

Keywords: trastuzumab, CNS metastases, breast cancer, .

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Does trastuzumab increase the risk of isolated CNS metastases in patients with breast cancer?

Research shows that brain metastasis of breast cancer may occur more often in women with HER2 overexpression. These patients require more aggressive surveillance to identify disease earlier, and new therapies are needed that can overcome barriers to effective CNS drug delivery.

» Robert J Weil

 
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